Hydrogen gas has been found to activate PGC-1a, which enhances mitochondrial activity. In cancer patients with Stage IV colorectal carcinoma, PD-1-expressing CD8+ T cells in the peripheral blood have been associated with poor prognosis due to mitochondrial dysfunction and low PGC-1a levels. However, treatment with hydrogen gas has been found to reduce the proportion of terminal PD-1+ CD8+ T cells, leading to an improvement in patient prognosis. The ratio of terminal PD-1+ CD8+ T cells after hydrogen gas treatment to before treatment has been found to be an independent factor predicting progression-free survival and overall survival. Additionally, a combination therapy of hydrogen gas and nivolumab has shown to be more effective in improving patient outcomes than nivolumab alone. Therefore, hydrogen gas may offer potential benefits for cancer patients by improving mitochondrial activity and reducing the proportion of terminal PD-1+ CD8+ T cells, which can ultimately improve prognosis.
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Hong Kong's first free hydrogen inhalation experience store
Free trial ️️| Share Hydrogen to the society
Appointments are required, time slots are limited, first-served, first-served, please be on time.
Address: Room 1008, 10th Floor, Arion Commercial Center, 2-12 Queen's Road West, Sheung Wan, Hong Kong
Time: 12-8 pm (45 minutes per session)
Fee: free
Appointment: WhatsApp 90799668
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